This study aims to determine whether the Islamic Human Development Index I-HDI) affects the number of poor people in Bone Regency, South Sulawesi Province (2011-2021). How does the Islamic Human Development Index (I-HDI) influence the number of poor people in Bone District, South Sulawesi Province, from the perspective of Maqashid al-Shariah? To obtain data from the problem above, the researchers used secondary data obtained from the official website of the Bone Regency Central Bureau of Statistics (BPS) (bonekab.bps.go.id) and the official website of the South Sulawesi Province Central Statistics Agency (https://sulsel.bps.go.id/). To carry out data analysis in this study, researchers used the Eviews 10 application. The result shows that the statistical probability value of variable x is 0.0037, less than 0.05 (0.0037 <0.005), and the statistical t value is -3.89. It can be concluded that the I-HDI variable has a negative effect on the number of poor people. Changes in the I-HDI variable will change the number of poor people by -14.24445%. The R-Squarer value indicates the effect of the independent variable on the dependent variable of 62.73%. At the same time, the rest is influenced by other factors not explained in this study. Maqashid al-Shariah's conception that focuses on human welfare and poverty alleviation through increasing I-HDI is divided into 4 poverty alleviation stages: the social assistance development model, the community empowerment development model, and the business empowerment model. Micro. The poverty alleviation program by implementing Maqashid al-Shariah values ​​per the Maqashid al-Shariah principles is described in 5 basic concepts: protecting religion, reason, soul, offspring, and assets. Internalization of the values ​​of Maqashid al-Shariah in reducing poverty can be achieved to create benefits for the community.