This study aims to investigate the effects of socio-religious mediation on changes in café selection patterns among millennial Muslims. In terms of methodology, this research uses quantitative methods. Data collection using a questionnaire. The subjects of this study were 100 millennial Muslim respondents on the island of South Sulawesi, Indonesia. The existing respondents were determined by the main criteria: Muslims aged 24-39 years who represent millennial Muslims. Data analysis and hypothesis testing were carried out through structural equation models and multiple regression. The software (Smart PLS version 24) is used for statistical data processing. The results showed that the mediation of socio-religious behavior was found in the relationship between religiosity, attitudes, and changes in café selection patterns. In contrast, socio-religious behavior was also to partially mediate the relationship between subjective norms, perceptions of behavioral control and changes in cafe selection patterns. In other words, the model proposed to form a fundamental change in the pattern of choosing millennial Muslim cafes is not running optimally. However, this study still finds it important that socio-religious behavior can mediate the relationship between changes in religiosity, attitudes, and cafe selection patterns.