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Case Fever Dengue Hemorrhagic Fever (DHF) since the year 2019 amounts to 138.127 cases, w    hich is increased a year previously in the year 2018 as much as 65,602 cases  in Indonesia. In 2020, the number of dengue fever cases in Gowa Regency increased to 387 cases, with six people dying from dengue fever and becoming the city with the highest number of dengue fever cases in South Sulawesi Province. One of the factors causing the increase in DHF is climate. The study aims to know the climate connection factor (Temperature, air, Rainfall, rain, air humidity, air pressure, wind speed, and rainy days) with the occurrence of DHF in the Gowa Regency in 2017-2021. This study used a descriptive design. Ecological survey with a time series approach (time series analysis). Samples of study This is all over results observation monthly from incident dengue fever, temperature air,rainfall, air humidity, air pressure, wind speed, and rainy days, in 5 years that is 60 months taken from data secondary/result observation. The results of this study indicate that there is no relationship between air temperature (p=0.199), air humidity (p=0.160), air pressure (p=0.191), and also day Rain (p=0.051) with incident dengue fever. There is a connection between rainfall (p=0.024) and wind speed (p=0.043) with incident dengue fever. This research suggests the need for public awareness and participation in efforts to prevent and eradicate dengue fever.