Zingiber zerumbet is a member of the Zingiberaceae family with various therapeutic potentials. This study aims to determine the phytochemical compounds in the ethyl acetate-soluble and n-hexane-soluble fractions of the Zingiber zerumbet rhizome and its antioxidant potential. Identification of secondary metabolite content using the chemical reaction method of the alkaloids, saponins, flavonoids, polyphenols, tannins, and steroids/triterpenoids. Meanwhile, the potential antioxidant assay was carried out based on its ability to reduce DPPH free radicals. The test results revealed the presence of polyphenolic/tannin content in the ethyl acetate-soluble fraction and alkaloids and flavonoids in the n-hexane-soluble fraction. These findings are directly proportional to the free radical scavenging activity of ethyl acetate-soluble fractions, n-hexane-soluble fractions, and vitamin C (standard antioxidant), 69,476; 77.780, and 7.79 ppm, respectively. These findings suggest that both fractions are suitable natural antioxidant sources.